Large ribosomal subunit protein uL1
Also known as: M5005_Spy0375, SPy_0461, rplA
Function
Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
Classification
- Family (Pfam)
- PF00687 Ribosomal_L1
- InterPro
- Ribosom_uL1_bact, Ribosomal_uL1, Ribosomal_uL1-like, Ribosomal_uL1/biogenesis, Ribosomal_uL1_3-a/b-sand, Ribosomal_uL1_CS
- Functional cluster
- Glycolytic Enzymes & Elongation Factor Ts
Gene Ontology · 6
Drugs targeting this protein · 1
- RETAPAMULIN inhibitor
Related proteins · sequence + function similarity
- Large ribosomal subunit protein uL1 1.00
- Large ribosomal subunit protein uL1 1.00
- Large ribosomal subunit protein uL1 1.00
- Large ribosomal subunit protein uL1 1.00
- Large ribosomal subunit protein uL1 1.00
- Large ribosomal subunit protein uL1 1.00
- Large ribosomal subunit protein uL1 1.00
- Large ribosomal subunit protein uL1 1.00
- Large ribosomal subunit protein uL1 1.00
- Large ribosomal subunit protein uL1 1.00
- Large ribosomal subunit protein uL1 0.99
- Large ribosomal subunit protein uL1 0.99
Literature · 2 cited papers
- Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events. J. Infect. Dis. · 2005
- Complete genome sequence of an M1 strain of Streptococcus pyogenes. Proc. Natl. Acad. Sci. U.S.A. · 2001
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