Large ribosomal subunit protein bL12
Also known as: M5005_Spy0796, SPy_1073, rplL
Function
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
Classification
- Family (Pfam)
- PF00542 Ribosomal_L12, PF16320 Ribosomal_L12_N
- InterPro
- Ribosomal_bL12, Ribosomal_bL12_C, Ribosomal_bL12_C/ClpS-like, Ribosomal_bL12_oligo, Ribosomal_bL12_oligo_N_sf
- Functional cluster
- Ribosomal Protein L12 & Acyl Carriers
Gene Ontology · 4
Drugs targeting this protein · 1
- RETAPAMULIN inhibitor
Related proteins · sequence + function similarity
- Large ribosomal subunit protein bL12 1.00
- Large ribosomal subunit protein bL12 1.00
- Large ribosomal subunit protein bL12 1.00
- Large ribosomal subunit protein bL12 1.00
- Large ribosomal subunit protein bL12 1.00
- Large ribosomal subunit protein bL12 1.00
- Large ribosomal subunit protein bL12 1.00
- Large ribosomal subunit protein bL12 0.99
- Large ribosomal subunit protein bL12 0.99
- Large ribosomal subunit protein bL12 0.99
- Large ribosomal subunit protein bL12 0.99
- Large ribosomal subunit protein bL12 0.99
Literature · 2 cited papers
- Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events. J. Infect. Dis. · 2005
- Complete genome sequence of an M1 strain of Streptococcus pyogenes. Proc. Natl. Acad. Sci. U.S.A. · 2001
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