Large ribosomal subunit protein uL15

UniProt P0A0F8 Organism Staphylococcus aureus (strain NCTC 8325 / PS 47) Gene SAOUHSC_02492, rplO

Also known as: SAOUHSC_02492, rplO

Function

Binds to the 23S rRNA.

Classification

Family (Pfam): PF00828 Ribosomal_L27A
InterPro: Ribosomal_uL15, Ribosomal_uL15/eL18, Ribosomal_uL15/eL18_sf, Ribosomal_uL15_bact, Ribosomal_uL15_CS
Functional cluster: Large Ribosomal Subunit Proteins

Experimental structures · PDB · 31

4WCE X-ray 3.53A
4WF9 X-ray 3.43A
4WFA X-ray 3.39A
4WFB X-ray 3.43A
5HKV X-ray 3.66A
5HL7 X-ray 3.55A
5LI0 EM 3.80A
5ND8 EM 3.70A
5ND9 EM 3.70A
5NRG X-ray 3.44A
5TCU EM 3.90A
6DDD EM 3.10A
… and 19 more

A predicted model is available from AlphaFold.

Gene Ontology · 4

GO:0022625 cytosolic large ribosomal subunit
GO:0019843 rRNA binding
GO:0003735 structural constituent of ribosome
GO:0006412 translation

Drugs targeting this protein · 1

RETAPAMULIN inhibitor

Related proteins · sequence + function similarity

Large ribosomal subunit protein uL15 1.00
Large ribosomal subunit protein uL15 1.00
Large ribosomal subunit protein uL15 1.00
Large ribosomal subunit protein uL15 1.00
Large ribosomal subunit protein uL15 1.00
Large ribosomal subunit protein uL15 1.00
Large ribosomal subunit protein uL15 1.00
Large ribosomal subunit protein uL15 1.00
Large ribosomal subunit protein uL15 1.00
Large ribosomal subunit protein uL15 1.00
Large ribosomal subunit protein uL15 1.00
Large ribosomal subunit protein uL15 1.00

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