Roxadustat
SMILES Cc1nc(C(=O)NCC(=O)O)c(O)c2ccc(Oc3ccccc3)cc12
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 4 targets
- Prolyl hydroxylase EGLN2 Q96KS0 · inhibitor · Hypoxia-inducible factor prolyl hydroxylase inhibitor
- Transmembrane prolyl 4-hydroxylase Q9NXG6 · inhibitor · Hypoxia-inducible factor prolyl hydroxylase inhibitor
- Egl nine homolog 1 Q9GZT9 · inhibitor · Hypoxia-inducible factor prolyl hydroxylase inhibitor
- Prolyl hydroxylase EGLN3 Q9H6Z9 · inhibitor · Hypoxia-inducible factor prolyl hydroxylase inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.