Thalidomide
SMILES O=C1CCC(N2C(=O)c3ccccc3C2=O)C(=O)N1
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 4 targets
- Protein cereblon Q96SW2 · inhibitor · CRL4(CRBN) E3 ubiquitin ligase inhibitor
- DNA damage-binding protein 1 Q16531 · inhibitor · CRL4(CRBN) E3 ubiquitin ligase inhibitor
- Cullin-4A Q13619 · inhibitor · CRL4(CRBN) E3 ubiquitin ligase inhibitor
- E3 ubiquitin-protein ligase RBX1 P62877 · inhibitor · CRL4(CRBN) E3 ubiquitin ligase inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.