Refametinib
SMILES COc1cc(F)c(F)c(Nc2ccc(I)cc2F)c1NS(=O)(=O)C1(C[C@H](O)CO)CC1
Structure
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 2 targets
- Dual specificity mitogen-activated protein kinase kinase 1 Q02750 · inhibitor · Dual specificity mitogen-activated protein kinase kinase 1 inhibitor
- Dual specificity mitogen-activated protein kinase kinase 2 P36507 · inhibitor · Dual specificity mitogen-activated protein kinase kinase 2 inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.