Larotrectinib
SMILES O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC[C@H](O)C1
Structure
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 3 targets
- High affinity nerve growth factor receptor P04629 · inhibitor · Neurotrophic tyrosine kinase receptor inhibitor
- BDNF/NT-3 growth factors receptor Q16620 · inhibitor · Neurotrophic tyrosine kinase receptor inhibitor
- NT-3 growth factor receptor Q16288 · inhibitor · Neurotrophic tyrosine kinase receptor inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.