Trametinib
SMILES CC(=O)Nc1cccc(-n2c(=O)n(C3CC3)c(=O)c3c(Nc4ccc(I)cc4F)n(C)c(=O)c(C)c32)c1
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 2 targets
- Dual specificity mitogen-activated protein kinase kinase 2 P36507 · inhibitor · Dual specificity mitogen-activated protein kinase kinase; MEK1/2 inhibitor
- Dual specificity mitogen-activated protein kinase kinase 1 Q02750 · inhibitor · Dual specificity mitogen-activated protein kinase kinase; MEK1/2 inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.