Navtemadlin
SMILES CC(C)[C@@H](CS(=O)(=O)C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 2 targets
- Cellular tumor antigen p53 P04637 · inhibitor · Tumour suppressor p53/oncoprotein Mdm2 inhibitor
- E3 ubiquitin-protein ligase Mdm2 Q00987 · inhibitor · Tumour suppressor p53/oncoprotein Mdm2 inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.