Palbociclib
SMILES CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 4 targets
- G1/S-specific cyclin-D1 P24385 · inhibitor · CDK6/cyclin D1 inhibitor
- Cyclin-dependent kinase 6 Q00534 · inhibitor · CDK6/cyclin D1 inhibitor
- Cyclin-dependent kinase 4 P11802 · inhibitor · Cyclin-dependent kinase 4/cyclin D1 inhibitor
- G1/S-specific cyclin-D1 P24385 · inhibitor · Cyclin-dependent kinase 4/cyclin D1 inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.